Arstiteaduskonnas kaitstud doktoritööd
Kaire Innos "Epidemiological resources in Estonia: Data sources, their quality and the feasibility of cohort studies"
Jana Kivastik "Lung Function in Estonian Schoolchildren: Relationship with Anthtopometric Indices and Respiratory Symptoms, Reference values for Dynamic Respirometry"
Karin Kull "Inflammatory bowel disease: an immunogenetic study"
Eve-Irene Lepist "Oral peptide prodrugs � studies on stability and absorption"
Ruth Kalda "Structure and outcome of family practice quality in the changing health care system of Estonia"
Annika Krüüner "Mycobacterium tuberculosis - spread and drug resistance in Estonia"
Anneli Uusküla "Epidemiology of sexually transmitted diseases in Estonia in 1990 to 2000"
Marlit Veldi "Obstructive sleep apnoea: Computerized Endopharyngeal Myotonometry of the Soft Palate and Lingual Musculature"
Tamara Vorobjova "Immune response to Helicobacter pylori and its association with dynamics of chronic gastritis and epithelial cell turnover in antrum and corpus"
Heidi Annuk "Selection of medicinal plants and intestinal lactobacilli as antimicrobial components for functional foods"
Maigi Eisen "Pathogenesis of contact dermatitis: participation of oxidative stress. A clinical-biochemical study"
Piret Hussar "Histology of the post-traumatic bone repair in rats. Elaboration and use of a new standardized experimental model - bicortical perforation of tibia compared to internal fracture and resection osteotomy"
Ade Kallas "Characterization of antibodies to coagulation factor VIII"
Aet Lukmann "Early rehabilitation of patients with ischaemic heart disease after surgical revascularization of the myocardium: assessment of health-related quality of life, cardiopulmonary reserve and oxidative stress. A clinical study"
Tõnu Rätsep "Aneurysmal subarachnoidhaemorrhage: Noninvasive monitoring of cerebral haemodynamics"
Marju Herodes "Quality of life of people with epilepsy in Estonia"
Ingrid Kalev "CC - chemokine receptor 5 (CCR5) gene polymorphism in Estonians and in patients with type I and type II diabetes mellitus"
Kersti Klaamas "Humoral immune response to Helicobacter pylori: a study of host-dependent and microbial factors"
Helgi Kolk "Dyspepsia and Helicobacter pylori infection: The diagnostic value of symptoms, treatment and follow-up of patients referred for upper gastrointestinal endoscopy by family physicians"
Krista Lõivukene "Helicobacter pylori in gastric microbial ecology and its antimicrobial susceptibility pattern"
Katre Maasalu "Changes in bone quality due to age and genetic disorders and their clinical expressions in Estonia"
Kersti Oselin "Studies on the human MDR1, MRP1, and MRP2 ABC transporters: Functional relevance of the genetic polymorphisms in the MDR1 and MRP1 gene"
Margot Peetsalu "Long-term follow-up after vagatomy in duodenal ulcer disease: recurrent ulcer, changes in the function, morphology, and Helicobacter pylori colonisation of the gastric mucosa"
Leena Puksa "Late responses in motor nerve conductions studies. F and A waves in normal subjects and patients with neuropathies"
Toomas Sillakivi "Perforated peptic ulcer in Estonia: Epidemiology, risk factors and relations with Helicobacter pylori"
Helena Soomer "Validation of identification and age estimation methods in forensic odontology"
Jaan Soplepmann "Peptic ulcer haemorrhage in Estonia: epidemiology, prognostic factors, treatment and outcome"
Pille Taba "Epidemiology of Parkinson's disease in Estonia: Prevalence, incidence, clinical characteristics, and pharmacoepidemiology"
Alar Veraksit¨ "Characterization of behavioural and biochemical phenotype of cholecystokinin-2 receptor deficient mice: changes in function of dopamine- and endopioidergic system"
Mari Järvelaid "Health damaging risk behaviours in adolescence"
Lumme Kadaja "Molecular approach to the regulation of mitochondrial function in oxidative muscle cells"
Andres Kulla "Molecular characteristics of mesenchymal stroma in human astrocytic gliomas"
Tuuli Käämbre "Intracellular energetic unit: structural and functional aspects"
Aive Liigant "Epidemiology of primary central nervous system tumours in Estonia from 1986 to 1996. Clinical characteristics, incidence, survival and prognostic factors"
Eduard Maron "Serotonin function in panic disorder: from clinical experiments to brain imaging and genetics"
Ülle Pechter "Progression prevention strategies in chronic renal failure and hypertension. An experimental and clinical study"
Aune Rehema "Assessment of nonhaem ferrous iron and glutathione redox ratio as markers of pathogeneticity of oxidative stress in different clinical groups"
Evelin Seppet "Interaction of mitochondria and ATPases in oxidative muscle cells in normal and pathological conditions"
Gunnar Tasa "Polymorphic glutathione S-transferases - biology and role in modifying genetic susceptibility to senile cataract and primary open angle glaucoma"
Vitali Vassiljev "Influence of nitric oxide synthase inhibitors on the effects of ethanol after acute and chronic ethanol administration and withdrawal"
Marje Oona "Helicobacter pylori infection in children: epidemiological and therapeutic aspects"
Kersti Kokk "Regulation of active and passive molecular transport in the testis"
Vladimir Järv "Cross-sectional imaging for pretreatment evaluation and follow-up of pelvic malignant tumors"
Külli Kingo "The interleukin-10 family cytokines gene polymorphisms in plaque psoriasis"
Mati Merila "Anatomy and clinical relevance of the glenohumeral joint capsule and ligaments"
Piibe Muda "Hypertension and homocysteine: Associations between essential hypertension and homocysteine in treated and untreated hypertensive patients with and without coronary artery disease"
Andre Õun "Epidemiology of adult epilepsy in Tartu, Estonia: Incidence, prevalence and medical treatment"
Sirli Raud "Cholecystokinin2 receptor deficient mice: changes in function of gaba-ergic system"
Epp Songisepp "Evaluation of technological and functional properties of the new probiotic lactobacillus fermentum ME-3"
Tiia Ainla "Acute myocardial infraction in estonia: Clinical characteristics, management and outcome"
Tiia Tamme "Epidemiology of odontogenic tumors in Estonia. Pathogenesis and clinical behaviour of ameloblastoma"
Kati Koido "Singlenucleotide polymorphism profiling of 22 candidate genes in mood and anxiety disorders"
Andres Sell "Determing the minimum spinal local anaesthetic reqiurements for hip replacement surgery - a study employing spinal catheter"
Priit Kasenõmm "Indicators for tonsillectomy in adults with recurrent tonsillitis - clinical, microbiological and patomorphological investigations"
Triine Annus "Allergy in Estonian schoolchildren: time trends and characteristics of manifestations"
Tiia Voor "Microorganisms in infancy and development of allergy: comparison of Estonian and Swedish children"
Eva ´usinaite "Hepatitis C virus: genotype identification and interactions between viral proteases"
Džamilja Safiulina "The studies of mitochondria in cultured cerebellar granule neurons: characterization of mitochondrial function, volume homeostasis and interaction with neurosteroids"
Piret Kõll "Oral Lactoflora in Chronic Parodontitis and Periodontal helath"
Tiina Stelmach "Epidemiology of cerebral palsy and unfavourable neurodevelopmental outcome based on child population of Tartu city and county, in Estonia: prevalence, clinical features and risk factors"
Külli Jaako "Studies on the role of neurogenesis in brain plasticity"
Aare Märtson "Lower limb lengthening: studies on bone regeneration and long-term clinical results"
Katrin Pudersell "Tropane alcaloid production and riboflavine excretion in the field and tissue cultures of henbane (Hyoscyamus niger L.)"
Stanislav Liskmann "Peri-implant disease: pathogenesis, diagnosis and treatment in view of both inflammation and oxidative stress profiling"
Heli Tähepõld "Patient consultation in family medicine"
Ruth Rudissaar "Nerupharmacology of atypical antipsychotics and an animal model of psychosis"
Helena Andreson "Diversity of Helicobacter pylori genotypes in Estonian patients with chronic inflammatory diseases"
Tarmo Areda "Behavioural and neurogenetic study of mechanisms related to cat odour induced anxiety in rodents"
Aleksei Nelovkov "Behavioural and neurogenetic study of molecular mechanisms involved in regulation of exploratory behaviour in rodents"
Katrin Pruus "Mechanism of action of antidepressants: aspects of serotoninergic system and its interaction with glutamate"
Priit Põder "Clinical and experimental investigation: Relationship of ischaemia/reperfusion injury with oxidative stress in abdominal aortic aneurysm repair and in extracranial brain artery endarterectomy and possibilities of protection against ischaemia using a glutathione analogue in a rat model of global brain ischaemia"
Marika Tammaru "Patient-reported outcome measurement in rheumatoid arthritis"
Tiia Reimand "Down syndrome in Estonia"
Diva Eensoo "Risk-taking in traffic and markers of risk-taking behaviour in schoolchildren and car drivers"
Riina Vibo "The third stroke registry in Tartu, Estonia from 2001 to 2003: incidence, case-fatality, risk factors and long-term outcome"
Eve Õiglane-Slik "Angelman and Prader-Willi syndromes in Estonia"
Chris Pruunsild "Juvenile idiopathic arthritis in children in Estonia"
Kadri Haller "Antibodies to follicle stimulating hormone. Significance in female infertility"
Pille Ööpik "Management of depression in family medicine"
Priit Kampus"Impact of Inflammation, oxidative stress and age on arterial stiffness and carotid artery intima-media thickness"
Jaak Kals "Endothelial function and arterial stiffness in patients with atherosclerosis and in healthy subjects. A clinical and bichemical study"
Alar Toom "Heterotopic ossification after total hip arthroplasty: clinical and pathogenetic investigation"
Annika Vaarmann "The studies of cystatin B deficient mice: neurochemical and behavioural alterations in animal model of progressive myoclonus epilepsy of Uverricht-Lundborg type"
Juri Karjagin "The pharmacokinetics of metronidazole and meropenem in severe sepsis. A microdialysis study."
Lea Pehme "Epidemiology of tuberculosis in Estonia 1991-2003 with special regard to extrapulmonary tuberculosis and delay in diagnosis of pulmonary tuberculosis"
Margus Punab "Male fertility and its risk factors in Estonia"
Tarvo Rajasalu "Autoimmune diabetes: immunological study of type 1 diabetes in humans and in experimental diabetes (RIP-B7.1) mouse model"
Peeter Padrik "Renal cell carcinoma: changes in natural history and treatment of metastatic disease"
Inga Talvik "Inflicted traumatic brain injury/shaken baby syndrome in Estonia- epidemiology and outcome"
Inga Karu "Ischaemia-reperfusion injury of the heart during coronary surgery: a clinical study investigating the effect of hyperoxia"
Neve Vendt "Iron deficiency and iron deficiency anaemia in infants aged 9 to 12 months in Estonia"
Annika Reintam "Gastrointestinal failure in intensive care patients"
Paul Korrovits "Asymptomatic inflammatory prostatitis: prevalence, etiological factors, diagnostic tools"
Karin Kogermann "Understanding solid-state transformations during dehydration: new insights using vibrational spectroscopy and multivariate modeling"
Lenne-Triin Heidmets "The effects of neurotoxins on brain plasticity: focus on neural cell adhesion molecule"
Kristiina Roots " Cationic regulation of Na-pump in the normal, Alzheimer's and CCK2 receptor-deficient brain"
Urho Abramov "Sex and environmental factors for the behavioural studies in phenotype of mice lacking CCK2 receptors: implication for the behavioural studies in transgenic lines"
Helen Puusepp "The genetic causes of mental retardation in Estonia: fragile X syndrome and creatine transporter defect"
Kristiina Rull "Human chorionic gonadotropin beta genes and recurrent miscarriage: expression and variation study"
Margus Eimre "Organization of energy transfer and feedback regulation in oxidative muscle cells."
Hendrik Luuk "Distribution and behavioral effects of Wfs1 protein in the central nervous system."
Maire Link "Transcription factors FoxP3 and AIRE: autoantibody associations"
Kai Haldre "Sexual health and behavior of young women in Estonia."
Kaur Liivak "Classical form of congenital adrenal hyperplasma due to 21-hydroxylase deficiency in Estonia: incidence, genotype and phenotype with specialattention to short-term growth and 24-hour blood pressure"
Anne Must "Studies on molecular genetics of male completed suicide in Estonian population"
Kersti Ehrlich "Antioxidative glutathione analogues (UPF peptiides)- molecular design, structure-activity relationships and testing the protective properties"
Anneli Rätsep "Type 2 diabetes care in family medicine"
Kaido Kurrikoff "Involvement of cholecystokinin in chronic pain mechanisms and endogenous antinociception"
Silver Türk "Etiopathogenic aspects of chronic prostatitis: role of mycoplasmas, coryneform bacteria and oxidative stress"
Kaire Heilman "Risk markers for cardiovascular disease and low bone mineral density in children with type I diabetes"
Kristi Rüütel "HIV-epidemic in Estonia: injecting drug use and quality of life of people living with HIV"
Triin Eller "Immune markers in major depression and in antidepressive treatment"
Siim Suutre "The role of TGF-ß isoforms and osteoprogenitor cells in the pathogenesis of heterotopic ossification. An experimental and clinical study of hip arthroplasty"
Kai Kliiman "Highly drug-resistant tuberculosis in Estonia: Risk factors and predictors of poor treatment outcome"
Inga Villa "Cardiovascular healt-related nutrition, physical activity and finess in Estonia"
Anu Aonurm-Helm "Depression-like phenotype and altered intracellular signalling in neural cell adhesion molecule (NCAM)-deficient mice"
Tõnis Org "Molecular function of the first PHD finger domain of Autoimmune Regulator protein"
Tuuli Metsvaht "Optimal antibacterial therapy of neonates at risk of early onset sepsis"
Silva Sütt " Role of endocannabinoid system and Wfs1 in regulation of emotional behavior: behavioural, pharmacological and genetic studies"
Koit Reimand "Autoimmunity in reproductive failure: A study on associated autoantibodies and autoantigens"
Jaanus Kahu "Kidney transplantation: Studies on donor risk factors and mycophenolate mofetil"
Rael Laugesaar "Paediatric stroke in Estonia: epidemiology and risk factors"
Mart Kull "Impact of vitamin D and hypolactasia on bone mineral density: a population based study in Estonia"
Mari-Anne Philips "Characterization of Myg1 gene and protein: expression patterns, subcellular localization, gene deficient mouse and functional polymorphisms in human"
Mark Braschinsky "Epidemiology and quality of life issues of hereditary spastic paraplegia in Estonia and implemention of genetic analysis in everyday neurologic practice"
Kadri Suija "Major depression in family medicine: associated factors, recurrence and possible intervention"
Jarno Habicht "Health care utilisation in Estonia: socioeconomic determinants and financial burden of out-of-pocket payments"
Kristi Abram "The prevalence and risk factors of rosacea. Subjective disease perception of rosacea patients"
Malle Kuum "Mitochondrial and endoplasmic reticulum cation fluxes: novel roles in cellular physiology"
Rita Teek "The genetic causes of early onset hearing loss in Estonian children"
Daisy Volmer "The development of community pharmacy services in Estonia -public and professional perceptions 1993-2006"
Ranno Rätsep "Genetics of psoriasis and vitiligo, focus on IL10 family cytokines"
Jelena Lissitsina "Cytogenetic causes of male infertility"
Delia Lepik "Comaprison of gunshot injuries caused from Tokarev, Makarov and Glock 19 pistols at different firing distances"
Ene-Renate Pähkla "Factors related to the efficency of treatment of advanced periodontitis"
Maarja Krass "L-Arginine pathways and antidepressant action"
Taavi Lai "Population health measures to support evidence - based health policy in Estonia"
Tiit Salum "Similarity and difference of temperature -dependence of the brain sodium pump in normal, different neuropathological, and aberrant conditions and its possible reasons"
Tõnu Vooder "Molecular differences and similarities between histological subtypes of non-small cell lung cancer"
Jelena Št¨epetova "Characterization of intestinal Lactic acid bacteria bacteriological, biochemical and molecular approaches"
Radko Avi "Natural polymorphisms and transmitted drug resistance in Estonian HIV-1 CRF06_cpx and its recombinant viruses"
Edward Laane "Multiparameter flow cytometry in haematological malignancies "
Triin Jagomägi "A study of genetic etiology of nonsyndromic cleft lip and palate"
Ivo Laidmäe "Fibrin glue of tish (Salmon Salar) origin: immunological study and development of new phramaceutical preparation"
Ülle Parm "Early mucosal colonisation and its role in prdeiction of invasive infection in neonates at risk of early onset sepsis"
Kaupo Teesalu „Autoantibodies against desmin and transglutaminase 2 in celiac disease: diagnostic and functional significance“
Maksim Zagura „Biochemical, functional and structural profiling of arterial damage in atherosclerosis“
Vivian Kont ,,Autoimmune Regulator: Characterization of Thymic Gene Regulation and Promoter Methylation“
Pirje Hütt „Functional properties, persistence, safety and efficacy of potential probiotic lactobacilli”
Kairit Joost "Selective screening of metabolic diseases in Estonia: the application of new diagnostic methods"
Innar Tõru ,,Serotonergic modulation of CCK-4-induced panic“
Sigrid Vorobjov „Drug use, related risk behaviour and harm reduction interventions utilization among injecting drug users in Estonia: implications for drug policy“
Martin Serg „Therapeutic aspects of haemodynamics, arterial stiffness, and oxidative stress in hypertension“
Jaanika Kumm „Molecular markers of articular tissues in early knee osteoarthritis: a population-based longitudinal study in middle-aged subjects“
Monika Jürgenson „A complex phenotype in mice with partial or complete deficiency of the NCAM protein"
Kertu Rünkorg „Functional changes of dopamine, endopioid and endocannabinoid systems in CCK2 receptor deficient mice“
Ene Reimann „Description of the cytokines and cutaneous neuroendocrine system in the development of vitiligo"
Mai Blöndal „Changes in the baseline characteristics, management and outcomes of acute myocardial infarction in Estonia“
Jana Lass „Epidemiological and clinical aspects of medicines use in children in Estonia“
Kai Truusalu „Probiotic lactobacilli in experimental persistent Salmonella infection“
Oksana Jagur „Temporomandibular joint radiographic changes in relation to pain, bone characteristics and results of arthroscopic treatment“
Katrin Sikk „Manganese-ephedrone įntoxicatįon pathogenesįs of neurological damage and clinįcal symptomatology“
Kai Blöndal „Tuberculosis in Estonia with special emphasis on drug-resistance: notification rate, disease recurrence and mortality“
Marju Puurand "Oxidative phosphorylation in different diseases of gastric mucosa"
Jürgen Innos "Behavioural,pharmacological and neurochemical characterisation of limbic system-associated membrane protein (LSAMP) deficient mice"
Merit Lamp „Genetic susceptibility factors in endometriosis“
Liis Sabre „Epidemiology of traumatic spinal cord injury in Estonia. Brain activation in the acute phase of traumatic spinal cord injury“
Aili Tagoma „Immune activation in female infertility: Significance of autoantibodies and inflammatory mediators“
Raido Paasma „Clinical study of methanol poisoning: handling large outbreaks, treatment with antidotes, and long-term outcomes“
Kuldar Kaljurand „Prevalence of exfoliation syndrome in Estonia and its clinical significance“
Maire Karelson „Vitiligo: clinical aspects, quality of life and the role of melanocortin system in pathogenesis”
Erik Salum "Beneficial effects of vitamin D and angiotensin II receptor blocker on arterial damage"
Kaili Anier "The role of DNA methylation in the development of cocaine-induced behavioural sensitisation"
Anne Kleinberg "Major depression in Estonia: prevalence, associated factors, and use of health services"
Triin Eglit "Obesity, impaired glucose regulation, metabolic syndrome and their associations with high-molecular-weight adiponectin levels"
Kristi Huik „The influence of host genetic factors on the susceptibility to HIV and HCV infections among intravenous drug users“
Irina Kerna "The contribution of ADAM12 and CILP genes to the development of knee osteoarthritis"
Liina Tserel "Epigenetic profiles of monocytes, monocyte-derived macrophages and dendritic cells"
Kristo Ausmees "Reproductive function in middle-aged males: Associations with prostate, lifestyle and couple infertility status"
Liivi Maddison „Tissue perfusion and metabolism during intra-abdominal hypertension“
Ingrid Liiv „Autoimmune regulator protein interaction with DNA-dependent protein kinase and its role in apoptosis“
Kai Muru “Prenatal screening strategies, long term outcome of children with marked changes in maternal screening tests and the most common syndromic heart anomalies in Estonia”
Krista Ress „Childhood coeliac disease in Estonia, prevalence in atopic dermatitis and immunological characterisation of coexistence“
Maarika Liik "Cognitive functioning, perceived cognition, subjective complaints and symptoms of depression in patients with epilepsy: Neuropsychological assessment and SPET brain imaging study"
Kaja Rahu "Morbidity and mortality among Baltic Chernobyl cleanup workers: a register-based cohort study"
Klari Noormets "The development of diabetes mellitus, fertility and energy metabolism disturbances in a Wfs1-deficient mouse model of Wolfram syndrome"
Liis Toome "Very low gestational age infants in Estonia Measuring outcomes and insights into prognostic factors"
Ceith Nikkolo “Impact of different mesh parameters on chronic pain and foreign body feeling after open inguinal hernia repair”
Vadim Brjalin „Chronic hepatitis C: predictors of treatment response in Estonian patients“
Vahur Metsna „Anterior knee pain in patients following total knee arthroplasty: the prevalence, correlation with patellar cartilage impairment and aspects of patellofemoral congruence“
Marju Kase „Glioblastoma multiforme: possibilities to improve treatment efficacy“
Sten Ilmjärv „Estimating differential expression from multiple indicators“
Paula Reemann „The effects of microenvironment on skin cells“
Riina Runnel Oral health among elementary school children and the effects of polyol candies on the prevention of dental caries"
Triin Laisk-Podar „Genetic variation as a modulator of susceptibility to female infertility and a source for potential biomarkers“
Anna Klugman „Functionality related characterization of pretreated wood lignin, cellulose and polyvinylpyrrolidone for pharmaceutical applications“
Andres Lust "Water mediated solid state transformations of a polymorphic drug - effect on pharmaceutical product performance"
Made Laanpere " Factors influencing women's sexual health and reproductive choices in Estonia"
Tanel Visnapuu “Pharmacological and behavioral characterization of the monoaminergic and GABA-ergic systems of Wfs1-deficient mice”
Mailis Tõnisson „Clinical picture and biochemical changes in blood in children with acute alcohol intoxication“
Kadri Tamme „High volume haemodiafiltration (HVHDF) in treatment of severe sepsis – impact on pharmacokinetics of antibiotics and inflammatory response“
Kai Part "Sexual health of young people in estonia in a social context: the role of school-based sexuality education and youth-friendly counseling service"
Urve Paaver "New perspectives for the amorphization and physical stabilization of poorly water-soluble drugs and understanding their dissolution behaviour"
Aleksandr Peet "Intrauterine and postnatal growth in children with HLA-conferred susceptibility to type 1 diabetes"